Kidney disease, donation, and transplantation in East Africa
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Keywords

Risk factors
Kidney donation
Transplantation
Compensation to donors
Laws
Costs
Uganda
East Africa.

How to Cite

AYAMBA, P. M. (2021). Kidney disease, donation, and transplantation in East Africa. Journal of Social and Administrative Sciences, 8(2), 71–90. https://doi.org/10.1453/jsas.v8i2.2218

Abstract

Abstract. The burden of kidney failure remains largely underreported in East Africa. Health systems face numerous challenges including a lack of kidney registries, shortages of trained skilled healthcare workers, a lack of diagnostic support, a lack of equipment, and underdeveloped policies to govern the provision of treatment for kidney failure. Kidney transplantation, an effective treatment option against kidney failure, is underused primarily because of its cost and the lack of laws governing it. In this paper, the author discusses the salient issues affecting kidney donation and transplantation in East Africa.

Keywords. Risk factors, kidney donation, transplantation, compensation to donors, laws, costs, Uganda, East Africa.

JEL. I11, I18.

https://doi.org/10.1453/jsas.v8i2.2218
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References

Anthony, K. (2012). Remembering Dr. Joseph Murray, a surgeon who changed the world of medicine. Havard Health Publishing, Harvard Medical School (blog). [Retrieved from].

Babau, C., Kalyesubura, R., Okello, E., Kakande, B., Sebatta, E., Mungoma, M., & Mondo, C. (2015). Pattern and presentation of cardiac diseases among patients with chronic kidney disease attending a national referral hospital in Uganda. BMC Nephrology, 16, 126. doi. 10.1186/s12882-015-0128-z

Barker, C.F., & Markmann, J.F. (2013). Historical overview of transplantation. Cold Spring Harbor Perspectives in Medicine, 3(4), a014977. doi. 10.1101.cshperspect.a014977

Becker, G.S., & Elias, J.J. (2007). Introducing incentives in the market for live and cadaveric organ donation. Journal of Economic Perspectives 21(3), 3-24. doi. 10.1257/jep.21.3.3

Cobo, G., Hecking, M., Port, F.K., Exner,I., Lindholm, B., & Stenvinkel, P. (2016). Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and hemodialysis. Clinical Science 130(14), 1147–63. doi. 10.1042/CS20160047

Cockwell, P., & Fisher, L. (2020). The global burden of chronic kidney disease. The Lancet 395: 709. doi. 10.1016/S0140-6736(19)32977-0

Cosio, F.G., & Alamir, A. (1998). Patient survival after renal transplantation: the impact of dialysis pre-transplant. Kidney International, 53, 767–772. doi. 10.1046/j.1523-1755.1998.00787.x

David, D.A., Allison, W.P.,& Douglas, R.M. 2018. The impact of prolonged dialysis prior to renal transplantation. Clinical Transplantation, 32(6), e13260. doi. 10.1111/ctr.13260

Declaration of Istanbul. (2008). Participants in the International Summit of Transplant Tourism and Organ Trafficking convened by The Transplantation Society and International Society of Nephrology in Istanbul, Turkey, 30 April to 2 May 2008. The Declaration of Istanbul on Organ Trafficking and Transplant Tourism. Kidney International, 71(7), 854-859. doi. 10.4103%2F0971-4065.43686

Delmonico, F. (2008). The development of the Declaration of Istanbul on Organ Trafficking and Transplant Tourism. Nephrology Dialysis Transplantation, 23(11), 3381-3382. doi. 10.1093/ndt/gfn552

Elisabetta, V., & Giorgina, B.P. (2019). Chronic kidney disease. the complex history of the organization of long-term care and bioethics. International Journal of Environmental Research and Public Health, 16(5), 758. doi. 10.3390/ijerph16050785

Eriksen, B.O.,&Ingebretsen, C.O. (2006). The progression of chronic kidney disease: a 10 year population based study of the effects of age and gender. International Society of Nephrology, Kidney International 69: 375-382. doi. 10.1038/sj.ki.5000058

Etienne, M., Guillermo, G., Mehta. R.L., & Micheal, V.R. (20199. International Society of Nephrology 0 by 25 Project: lessons learned. Annals of Nutrition & Metabolism, 74(3), 45-50.

Frank,. M., Philip, J.H.,& Glenn, M.C. (2018). The terrible toll of the kidney shortage. Journal of the American Society of Nephrology, 29(12), 2775-2776. doi. 10.1681/ASN.2018101030

Freudenberg, N. (2016). Healthy-food procurement: using the public plate to reduce food insecurity and diet-related diseases. Lancet Diabetes Endocrinology, 4(5), 383–4. doi. 10.1016/S2213- 8587(16)00078-4

Furia, F.F., Shoo, J., & Ruggajo, P.J. (2019). Developing nephrology services in low income countries: a case of Tanzania. BMC Nephrology, 20, 378. doi. 10.1186/s12882-019-1568-7

Geraldo, Jr., B.S., Jose Reginaldo, P., Elvino, J.G.B., Geysa, M.N.F., & Elizabeth, F.D. (2017). Kidney involvement in malaria: an update. Journal of the Institute of Tropical Medicine of SaoPaulo, 59. e53. doi. 10.1590/S1678-9946201759053

Giles-Corti, B., Vernez-Moudon, A., Reis, R., Turrell, G., Dannenberg, A.L., & Badland, H. (2016). City planning and population health: a global challenge. The Lancet, 10(388), 2912–2924. doi. 10.1016/S0140-6736(16)30066-6

Global Burden of Disease Study 2013 Collaborators. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 386, 743–800. doi. 10.1016/s0140-6736(15)60692-4

Hammond, S. (n.d.). How Iran solved its kidney shortage, and we can too. Niskanen Center. [Retrieved from].

Heron, J.E., Bagnis, C.I., & Gracey, C.M. (2020). Contemporary issues and new challenges in chronic kidney disease amongst people living with HIV. BMCAIDS Research and Therapy 17(11). doi. 10.1186/s12981-020-00266-3

Jinsoo, M., Soon, K.K., Hye, W.J., Han J., Yeonkook, J.K., Minseok, H., & Gilwon, H. (2018). End-stage renal disease and risk of active tuberculosis: a nation-wide population-based cohort study. Journal of Korean Medical Science, 33(53), e341. doi. 10.3346%2Fjkms.2018.33.e341

Jiro, A., & Ikari, Y. (2017). Cardiovascular disease in patients with end-stage renal disease on hemodialysis. Annals of Vascular Diseases, 10(4), 327-337. doi. 10.3400%2Favd.ra.17-00051

Johnson, R.J., Stenvinkel, P., Jensen, T., Lanaspa. M.A., Roncal, C., & Song, Z. (2016). Metabolic and kidney diseases in the setting of climate change, water shortage, and survival factors. Journal of the American Society of Nephrology. 27(8), 2247–56. doi. 10.1681/ASN.2015121314

Kisanga, O.A., Fredrick, F., Ruggajo, P.J., & Maro, E.E. (2017). Renal transplantation in sub Saharan Africa: a case of Tanzania. Journal of Kidney, 6(2).

Korir, M. (2020). Kidney transplant is way cheaper than dialysis. The Standard (Nairobi), April 14. [Retrieved from].

Leticia, B., & Charlotte, R. (2012). Chronic kidney disease and hypertension: a destructive combination. U.S. Pharmacist, 37(6), 26-29.

Matas, A.J. (2011). The case of a regulated system of incentives for living kidney donation. Annals of the Royal College of Surgeons of England, 93(3), 188-190. doi. 10.1308%2Frcsann.2011.93.3.188a

McPhee, M., Arumainayagam, N., Clark, M. Burfitt, N., & DasGupta, R. (2015). Renal injury management in an urban trauma centre and implications for urological training. Annals of the Royal College of Surgeons of England, 97(3), 194–7. doi. 10.1308/003588414X14055925061117

Merab, E. (2017). New law for organ donation to ease transplant pain. Daily Nation (Nairobi). [Retrieved from].

Ministry of Health. Uganda. (2017). Health report. Kampala.

Mitra, M.M. (2012). The Iranian model of living renal transplantation. Kidney International. 82(6), 627-634. doi. 10.1038/ki.2012.219

Murray, C.J., Barber, R.M., Foreman, K.J., & Abbasoglu, O.A. (2015). GBD 2013. DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. The Lancet, 28(386), 2145–91. doi. 10.1016/S0140-6736(15)61340-X

Neema,C., Rogatus, K., Tulla, M., Emmanuel, A., Francisca, K.,Neema, K., Adolfine, H., Francis, F.F., & Rob, P. (2019). Prevalence and factors associated with renal dysfunction in children admitted at two hospitals in Northwestern Tanzania. BMC Nephrology, 20(79), doi. 10.1186/s12882-019-1254-9

Norton, J.M., Moxey-Mims, M.M., Eggers, P.W., Narva, A.S., Star, R.A.,& Kimmel, P. L. (2016). Social determinants of racial disparities in CKD. Journal of the American Society of Nephrology, 27(9), 2576–95. doi. 10.1681/ASN.2016010027

Phillip, J.H., Frank, M., Glenn, M.C., Thomas, G.P., & John, P.R. (2018). Would government compensation of living kidney donors exploit the poor? An empirical analysis. PLOS One 13(11). e0205655. doi. 10.1371/journal/pone.0205655

Randolph, T.B., David, L.K.,& Rigmar, O. (2013). The global organ shortage: economic causes, human consequences and policy responses. Independent Review: A Journal of Political Economy, 18(19).

Rashad, S.B. (2020). Malarial acute renal failure. Journal of the American Society of Nephrology. 11(11), 2147-2154. doi. 10.1681/asn.v11112147

Satel, S. (2011). Paid organ donation. Annals of the College of Surgeons of England, 93(3), 188. doi. 10.1308/rcsann.2011.93.3.188a

Satel, S. (2016). Vouchers and incentives can increase kidney donations and save lives. Stat (Web site), September 13. [Retrieved from].

Schiano, T.D., & Rhodes, R. (2010). Transplant tourism. Current Opinions in OrganTransplantation, 15, 245–248. doi. 10.1097/mot.0b013e328337353e

Sever, M.S., Vanholder, R., Ashkenazi, I., Becker, G., Better, O., & Covic, A. (2012). RDRTF of ISN Work Group on Recommendations for the Management of Crush Victims in Mass Disasters. Nephrology Dialysis Transplantation, 27 (Suppl 1): 1–67. doi. 10.1093/ndt/gfs156

Seyid, B.G., Fatemeh, H., Shokouh, S., & Seyid, S.B.M. (2015). Diabetes and end-stage renal disease: an article on new concepts. Journal of Renal Injury Prevention, 4(2), 28-32. doi. 10.12861%2Fjrip.2015.07

Shuzo, K., & Sumi, H. (2020). Can we still ignore renal replacement therapy in sub-Saharan Africa? All living beings are created equal. Renal Replacement Therapy, 6(5). doi. 10.1186/s41100-019-0243-6

Thomas, S. (2011). The origins of transplantation. The Lancet, 378(9800), 1372-1373. doi. 10.1016/s0140-6736(11)61601-2

Thuo, E., & Riro, M. (2019). NHIF should review its kidney policy. Daily Nation (Nairobi), March 12. [Retrieved from].

Vonesch, N., D’Ovidio, M.C., Melis, P., Remoli, M.E., & Ciufolini, M.G. (2016). Climate change, vector-borne diseases and working population. Annalidell’Istituto Superiore diSanità, 52(3), 397–405. doi. 10.4415/ann_16_03_11

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